Vaginal Estradiol Price: Every Listing We Could Read
As of November 6, 2026, vaginal estradiol costs from $13.21 for a cream tube at Cost Plus Drugs on a listing with no stock notice, plus shipping and your own prescription, and from $40 a month at Found (Vaginal estrogen cream alone, without insurance), an online program.
By Julian Caraulani, reviewed by Dr. A. Goher, MBBS · public prices read · links marked paid may earn us a commission; they never change the order
$40 a month · Vaginal estrogen cream alone, without insurance · checked 2026-11-02
Vaginal estradiol treats vaginal and urinary symptoms of menopause locally. It is sold as a cream or an insert. It does not replace systemic estrogen for hot flashes, so ask your clinician which form fits your symptoms.
Online programs
Every published plan a reader can pay as shown, lowest first. Each price was read on the program's own page.
| Program and plan | Per month | What it is | Checked | Link |
|---|---|---|---|---|
| FoundVaginal estrogen cream alone, without insurance | $40$119 per 3-month supply | Not stated | 2026-11-02 | Visit (paid link) |
| WinonaVaginal estrogen cream | $89refilled on request | Compounded | 2026-11-05 | Visit (paid link) |
Public cash listings at Mark Cuban Cost Plus Drug Company
Cheapest first, as published on the seller's pages. We earn nothing from these. A pack price is not a monthly price. The seller says: "Your final cost will include shipping and taxes, which vary by location."
| Listing | Price | Seller's stock note | Source |
|---|---|---|---|
| Vaginal cream 0.01%, one 42.5 g tube | $13.21 | No stock notice on the page | read 2026-11-06 |
| Vaginal tablet 10 mcg, 30 count supply | $87.42 | No stock notice on the page | read 2026-11-06 |
Questions
What is the price of vaginal estradiol?
As of November 6, 2026, vaginal estradiol costs from $13.21 for a cream tube at Cost Plus Drugs on a listing with no stock notice, plus shipping and your own prescription, and from $40 a month at Found (Vaginal estrogen cream alone, without insurance), an online program.
Why is a cash pharmacy price lower than a program's price?
Mark Cuban Cost Plus Drug Company sells the drug alone and needs a prescription from your own clinician. The seller says: "Your final cost will include shipping and taxes, which vary by location." A program's price usually includes the clinician visit and delivery, as each row states.
Do I need a prescription for vaginal estradiol?
Yes. Each program on this page includes a clinician review in its own process, and a cash pharmacy needs a prescription from your own clinician.
Do these prices tell me which strength to use?
No. A strength is listed only because each one is sold and priced separately. Your clinician decides what is right for you.
HRT Watchdog is for information only and is not medical advice. Hormone therapy has benefits and risks; talk to a licensed clinician about whether it is right for you. We list prices only, never doses.